Vice President, Global Head of Clinical Pharmacology & Quantitative Science at Genmab

At Genmab, we’re committed to building extra[not]ordinary futures together, by developing antibody products and pioneering, knock-your-socks-off therapies that change the lives of patients and the future of cancer treatment and serious diseases. From our people who are caring, candid, and impact-driven to our business, which is innovative and rooted in science, we believe that being proudly unique, determined to be our best, and authentic is essential to fulfilling our purpose.

Genmab is looking for a dynamic, science-driven people leader to head our Clinical Pharmacology & Quantitative Sciences team. Do you get excited by our well diversified pipeline with a variety of antibody formats, targets, mechanism of actions, and indications? Does building effective partnerships across functions and expertise areas come natural to you? And do you have the leadership qualities to translate organizational strategy into actionable functional plans? Then take this chance to come work with us at a fast-growing, international innovation powerhouse.

The Role

You will act as functional leader of our Clinical Pharmacology & Quantitative Sciences (CPQS) group, currently consisting of 25+ scientists. Our talented team covers a broad spectrum of capabilities, including Quantitative Systems Pharmacology, Quantitative Translational Pharmacology, Pharmacometrics and Clinical Pharmacology. As such, we drive critical decisions across the entire spectrum of drug development at Genmab, from Discovery to Late Clinical Development and beyond. The Head of Clinical Pharmacology & Quantitative Sciences (CPQS) will report to the Head of Translational and Quantitative Sciences. The position will represent CPQS in the Translational and Quantitative Sciences Leadership Team and lead strategic development of pre-clinical and clinical pharmacology strategies for Genmab’s development pipeline by creating strong internal and external collaborations. The Head of CPQS will focus on further developing the group, fostering a culture of continuous learning and improvement. This is an exciting opportunity to lead a passionate, high profile, high-impact Pharmacology team, and work in a highly dynamic and collaborative setting.

Responsibilities

• Build, oversee and lead delivery of pre-clinical and clinical pharmacology team across programs/processes around genesis of problem statements, planning, analytics, and communications of insights according to timelines, budget, operational procedures, regulations, guidelines, and quality standards

• Manage a team of 25+ scientists within Clinical Pharmacology and Quantitative Sciences (CPQS) comprising of Translational and Quantitative Science (TQS), Quantitative Systems Pharmacology (QSP), Clinical Pharmacology & Pharmacometrics groups

• Define long term strategy for clinical pharmacology and quantitative sciences across all business areas based on understanding of strategic objectives and enterprise-wide implications

• Manage pre-clinical activities for drug candidates through IND enabling studies in close collaboration with Translational Research, Toxicology, DMPK, and other functions

• Manage clinical pharmacology, QSP and pharmacometrics activities of clinical candidates through BLA submission and beyond in close collaboration with multi-disciplinary teams.

• Lead and oversee development and implementation of clinical pharmacology and quantitative sciences systems/processes and “best practices” for effective delivery and drive compliance

• Provide strategic and tactical leadership across all clinical pharmacology and quantitative sciences operations including governance oversight, functional risk management, and resolution of critical systemic issues

• Drive and foster, in CPQS, innovation and adoption of emerging technologies and approaches in line with long term functional/organizational roadmap

• Engage in strategic communication with board, executive leadership, cross-functional leadership, and external stakeholder networks to optimally influence organizational outcomes

• Define, monitor, and manage short-term and long-term CPQS budgets for achievement of team goals

• Establish and drive people management processes around performance management, engagement, and development - balancing people aspirations and business needs

About you

We expect you to have deep and specialized knowledge in the Pharmacology space, including hands-on experience with progressing innovative drugs through an industry pipeline towards regulatory approval. While your background might not encompass all CPQS expertise areas, you are open to embracing new tools and technologies to ensure we derive full value from our capabilities in CPQS. You are collaborative, communicative and a natural bridge-builder. You have previously led and developed mid-sized teams consisting of diverse and talented scientists. You are able to perform “science with purpose”, balancing scientific curiosity with pragmatism to ensure portfolio progression.

Requirements

• Ph.D. in Clinical Pharmacology, Pharmacology, Pharmacokinetics, or related field with 15+ years of post-doctoral experience in relevant technical area

• 10+ years of people/ functional management experience in relevant area, preferably in pharma/biotech industry

• Broad experience in therapeutic antibody R&D is required; experience in immune-oncology preferred

• Working knowledge of Health Authority and Regulatory guidelines for drug development

• Significant experience building and executing multi-year strategies; and overseeing multiple global transformational initiatives in complex, dynamic environments

• Significant experience with development of overall department/area strategy, operational management of plans with cross-functional teams, as well as budget planning & management

• Significant publication record in high-quality journals, references, and external presentations demonstrating relevant experience

• Proven performance in earlier role/comparable role including strategic oversight and strategic stakeholder management across levels internally and externally

• Experience leading and managing multi-disciplinary teams in a cross-functional and collaborative environment

• An innovative attitude coupled with a strong sense of practical execution

• The ability to work collaboratively as part of a team in a fast-paced dynamic environment

For US based candidates, the proposed salary band for this position is as follows:

$240,000.00---$400,000.00

The actual salary offer will carefully consider a wide range of factors, including your skills, qualifications, experience, and location. Also, certain positions are eligible for additional forms of compensation, such as bonuses.

About You

• You are passionate about our purpose and genuinely care about our mission to transform the lives of patients through innovative cancer treatment
• You bring rigor and excellence to all that you do. You are a fierce believer in our rooted-in-science approach to problem-solving
• You are a generous collaborator who can work in teams with diverse backgrounds
• You are determined to do and be your best and take pride in enabling the best work of others on the team
• You are not afraid to grapple with the unknown and be innovative
• You have experience working in a fast-growing, dynamic company (or a strong desire to)
• You work hard and are not afraid to have a little fun while you do so

Locations

Genmab leverages the effectiveness of an agile working environment, when possible, for the betterment of employee work-life balance. Our offices are designed as open, community-based spaces that work to connect employees while being immersed in our state-of-the-art laboratories. Whether you’re in one of our collaboratively designed office spaces or working remotely, we thrive on connecting with each other to innovate.

About Genmab

Genmab is an international biotechnology company with a core purpose guiding its unstoppable team to strive towards improving the lives of patients through innovative and differentiated antibody therapeutics. For more than 20 years, its passionate, innovative and collaborative team has invented next-generation antibody technology platforms and leveraged translational research and data sciences, which has resulted in a proprietary pipeline including bispecific T-cell engagers, next-generation immune checkpoint modulators, effector function enhanced antibodies and antibody-drug conjugates. To help develop and deliver novel antibody therapies to patients, Genmab has formed 20+ strategic partnerships with biotechnology and pharmaceutical companies. By 2030, Genmab’s vision is to transform the lives of people with cancer and other serious diseases with Knock-Your-Socks-Off (KYSO™) antibody medicines.

Established in 1999, Genmab is headquartered in Copenhagen, Denmark with locations in Utrecht, the Netherlands, Princeton, New Jersey, U.S. and Tokyo, Japan. 

Our commitment to diversity, equity, and inclusion

We are committed to fostering workplace diversity at all levels of the company and we believe it is essential for our continued success. No applicant shall be discriminated against or treated unfairly because of their race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), national origin, age, disability, or genetic information. Learn more about our commitments on our website. 

Genmab is committed to protecting your personal data and privacy. Please see our privacy policy for handling your data in connection with your application on our website https://www.genmab.com/privacy.

Please note that if you are applying for a position in the Netherlands, Genmab’s policy for all permanently budgeted hires in NL is initially to offer a fixed-term employment contract for a year, if the employee performs well and if the business conditions do not change, renewal for an indefinite term may be considered after the fixed-term employment contract.