Technical Development Scientist - Compass Consulting

Our client is a leading biotechnology company that discovers, develops, manufactures, and commercializes medicines to treat patients with serious or life-threatening medical conditions.  They are among the world's leading biotech companies, with multiple products on the market and a promising development pipeline.

Job Overview:

RMG, in the Cell Culture and Bioprocess Operations department, is responsible for providing support to pre-Early Stage Research to Early Development projects with high-throughput protein production from mammalian transient cultures. We are looking for a motivated candidate with cell culture and sterile technique experience to join our team to enable protein production and help advance our portfolio.

Key Responsibilities:

• Perform transient transfections in CHO and HEK293 cells in scales 1mL to 25L to support pipeline productions adhering to established protocols.
• Maintain seed train cell cultures in bioreactors and shake flasks.
• Operate liquid handlers - Tecan and Hamilton for automated processes.
• Operate wave bag reactors for productions and cell maintenance
• Maintain and troubleshoot key cell culture instruments such as Vi-Cell, Nova Flex2, Nova Flex, Cedex and bioreactors.
• Participate in troubleshooting production or platform processes.
• Participate in lab management and data management.
• Contribute to improving existing cell culture platforms and developing new platforms to deliver diverse protein and cellular reagents to enable a large number of research programs.
• The candidate must be highly self-motivated, organized, detail oriented and responsive to feedback.
• The candidate is expected to precisely follow written procedures, practice sterile technique, demonstrate accurate documentation skills, and report deviations in a timely manner.
• They should be able to work independently within guidelines and policies, with minimal guidance.

Qualifications:

• Required:
  • PhD (with 0-2yrs relevant experience) in Biotechnology, Chemistry, Biochemistry or related fields.
  • Suspension adapted mammalian cell culture (CHO and/or HEK293)
  • Excellent written and verbal communication skills, and have strong collaborative skills.
• Preferred:
  • State-of-the-art transient and stable protein expression experience
  • Relevant bioreactor experience
  • Hands-on experience with automation and liquid handlers like Tecan Freedom Evo and Hamilton Microlab Star.
  • Knowledge of cell biology, cell engineering, molecular biology, recombinant protein purification and protein characterization is preferred.

Qualifications:

• Required:
  • PhD (with 0-2yrs relevant experience) in Biotechnology, Chemistry, Biochemistry or related fields.
  • Suspension adapted mammalian cell culture (CHO and/or HEK293)
  • Excellent written and verbal communication skills, and have strong collaborative skills.
• Preferred:
  • State-of-the-art transient and stable protein expression experience
  • Relevant bioreactor experience
  • Hands-on experience with automation and liquid handlers like Tecan Freedom Evo and Hamilton Microlab Star.
  • Knowledge of cell biology, cell engineering, molecular biology, recombinant protein purification and protein characterization is preferred.