Sr. Scientist, Preclinical Development at MRL San Francisco LLC

Sr. Scientist, Preclinical Development

Prvd suprt in early dvlpmnt of biolgcs pipelne by evalutng critcl qualty atributs, selctng manufctrble drug candidts, ensurng efcient transitn of candidte molculs to earlystge prcess dvlpmnt team. Reqd: Mastr�s deg in Biochem, Biotech, Chemicl Engg, Biolgicl Engg or reltd fld+4 yrs rlvnt exp in biophrma indstry or Bachelr�s deg in Biochem, Biotech, Chemicl Engg, Biolgicl Engg or reltd fld+7 yrs rlvnt exp in biophrma indstry. Exp w/high thrughput bioreactr systm (eg Ambr15); exp w/bioreactr prductn &protin purifctn usng FPLC; exp usng data sci. tls (Spotfire, SIMCA) f/data anlysis & vsulztn. Strng undrstndng w/prductn cell line genrtn usng CHO systm & micrbial systms (eg Pichai pastoris); good undrstndng of anlytcl methds f/asesng critcl qulty atributs of biolgcs; knwldge in cultre mdia dvlpmnt & prcess optmztn; fmliarty w/molculr biolgy technqs incld DNA isolatn, primer dsgn, copy numbr estmtn usng ddPCR, Gibson cloning & Southrn blot. Telcomutng permitd. Mst hv prf of legl authrty to wrk in US. Salryrnge: $125K to $196,800/yr. Aply at MRL San Francisco LLC careersite:www.merck.com/careers, create prfile/submt CV f/JobReq#R282073. EOE.MRL San Francisco LLC is subsdiary of Merck&CoInc.