Senior Scientist Protein Engineer, Biotherapeutics - Boehringer Ingelheim
Ridgefield, CT
About the Job
Description
Boehringer Ingelheim is currently seeking a talented and innovative Senior Scientist to join the Biotherapeutics Discovery department located at our Ridgefield, CT facility. The position offers an exciting opportunity to engage in the discovery and molecular engineering of Biotherapeutics for unmet medical needs. This individual will be an integral member of the biotherapeutic Protein Engineering group, participating in efforts to identify fit for purpose multi-specific biologics and engineering therapeutic proteins for improved drug like properties. The candidate will act as a subject matter expert in protein engineering and help to drive internal capabilities towards an industry leading position. You will be expected to help drive a culture of excellence through successful project outcomes, advancement of scientific understanding, empowerment of staff and increased connection with the field through an external publication record and collaborative interactions within the industry.
As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development, and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the company's success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.
Duties & Responsibilities
• Plans and executes fit for purpose multi-specific biotherapeutic campaigns including molecular design, vector construction, and screening of constructs. Provides solutions for real world drug discovery hurdles to project teams.
• Engineers’ novel proteins for function, stability or developability through a combination of in-silico and throughput-based techniques. Develops a target profile which considers a deep understanding of the target biology as well as standards for developability.
• Familiar with advanced theory and current technologies in the field of protein engineering and make recommendations to management regarding the advancement of capabilities.
• Create a culture of excellence through continual process improvement, scientific curiosity, and empowerment; develop and maintain outside visibility.
• Demonstrate independent thinking, e.g. by proposing and implementing new experimental designs and concepts that contribute to research goals and reflect expert knowledge; identify potential patentable inventions.
• Demonstrate clear understanding of research team goals and work effectively toward achieving them; be able to participate as co-leader or representative on multiple project teams and contribute to defining expertise-related aspects of overall program goals.
• Mentors and develops scientific staff; executes experimental designs and oversees results of technicians and junior level scientists.
• Comply with all applicable regulations; ensures that work performed in area of responsibility is conducted in a safe and compliant manner; maintain proper records in accordance with SOPs and policies.
• Prepare clear technical reports, publications, and oral presentations; independently communicate results in the form of reports and or presentations; present responsibly and defend own work at scientific meetings; deliver project updates to senior level management.
• Contribute to departmental administration; demonstrate fiscal responsibility with respect to cost of experiments, technology, external collaborations, and travel.
Requirements
• Requires a PhD in related field or equivalent industry experience in related field.
• Requires an advanced knowledge of a technology employed in the skill center such as protein computational modeling, protein biophysics, protein expression/purification, protein binding assays, and/or understanding of protein-protein interfaces.
• Experience in bioinformatics, structural biology, or molecular modeling software is a plus. Ideally the candidate will have a track record of successful outcomes and demonstrate an understanding of key considerations shaping protein design.
• Requires project management ability and excellent written and oral presentation skills.
Desired Experience, Skills and Abilities:
• Needs experience in one or more of the skills listed above, along with knowledge of the skill center process and the ability to apply those skills to the process. Requires international travel and collaboration.
Eligibility Requirements:
• Must be legally authorized to work in the United States without restriction.
• Must be willing to take a drug test and post-offer physical (if required)
• Must be 18 years of age or older
Compensation Data
This position offers a base salary typically between $140,000 and $222,000. The position may be eligible for a role specific variable or performance-based bonus and or other compensation elements. For an overview of our benefits please click here. (https://www.boehringer-ingelheim.com/us/careers/benefits-rewards)
All qualified applicants will receive consideration for employment without regard to a person’s actual or perceived race, including natural hairstyles, hair texture and protective hairstyles; color; creed; religion; national origin; age; ancestry; citizenship status, marital status; gender, gender identity or expression; sexual orientation, mental, physical or intellectual disability, veteran status; pregnancy, childbirth or related medical condition; genetic information (including the refusal to submit to genetic testing) or any other class or characteristic protected by applicable law.
Boehringer Ingelheim is currently seeking a talented and innovative Senior Scientist to join the Biotherapeutics Discovery department located at our Ridgefield, CT facility. The position offers an exciting opportunity to engage in the discovery and molecular engineering of Biotherapeutics for unmet medical needs. This individual will be an integral member of the biotherapeutic Protein Engineering group, participating in efforts to identify fit for purpose multi-specific biologics and engineering therapeutic proteins for improved drug like properties. The candidate will act as a subject matter expert in protein engineering and help to drive internal capabilities towards an industry leading position. You will be expected to help drive a culture of excellence through successful project outcomes, advancement of scientific understanding, empowerment of staff and increased connection with the field through an external publication record and collaborative interactions within the industry.
As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development, and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the company's success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.
Duties & Responsibilities
• Plans and executes fit for purpose multi-specific biotherapeutic campaigns including molecular design, vector construction, and screening of constructs. Provides solutions for real world drug discovery hurdles to project teams.
• Engineers’ novel proteins for function, stability or developability through a combination of in-silico and throughput-based techniques. Develops a target profile which considers a deep understanding of the target biology as well as standards for developability.
• Familiar with advanced theory and current technologies in the field of protein engineering and make recommendations to management regarding the advancement of capabilities.
• Create a culture of excellence through continual process improvement, scientific curiosity, and empowerment; develop and maintain outside visibility.
• Demonstrate independent thinking, e.g. by proposing and implementing new experimental designs and concepts that contribute to research goals and reflect expert knowledge; identify potential patentable inventions.
• Demonstrate clear understanding of research team goals and work effectively toward achieving them; be able to participate as co-leader or representative on multiple project teams and contribute to defining expertise-related aspects of overall program goals.
• Mentors and develops scientific staff; executes experimental designs and oversees results of technicians and junior level scientists.
• Comply with all applicable regulations; ensures that work performed in area of responsibility is conducted in a safe and compliant manner; maintain proper records in accordance with SOPs and policies.
• Prepare clear technical reports, publications, and oral presentations; independently communicate results in the form of reports and or presentations; present responsibly and defend own work at scientific meetings; deliver project updates to senior level management.
• Contribute to departmental administration; demonstrate fiscal responsibility with respect to cost of experiments, technology, external collaborations, and travel.
Requirements
• Requires a PhD in related field or equivalent industry experience in related field.
• Requires an advanced knowledge of a technology employed in the skill center such as protein computational modeling, protein biophysics, protein expression/purification, protein binding assays, and/or understanding of protein-protein interfaces.
• Experience in bioinformatics, structural biology, or molecular modeling software is a plus. Ideally the candidate will have a track record of successful outcomes and demonstrate an understanding of key considerations shaping protein design.
• Requires project management ability and excellent written and oral presentation skills.
Desired Experience, Skills and Abilities:
• Needs experience in one or more of the skills listed above, along with knowledge of the skill center process and the ability to apply those skills to the process. Requires international travel and collaboration.
Eligibility Requirements:
• Must be legally authorized to work in the United States without restriction.
• Must be willing to take a drug test and post-offer physical (if required)
• Must be 18 years of age or older
Compensation Data
This position offers a base salary typically between $140,000 and $222,000. The position may be eligible for a role specific variable or performance-based bonus and or other compensation elements. For an overview of our benefits please click here. (https://www.boehringer-ingelheim.com/us/careers/benefits-rewards)
All qualified applicants will receive consideration for employment without regard to a person’s actual or perceived race, including natural hairstyles, hair texture and protective hairstyles; color; creed; religion; national origin; age; ancestry; citizenship status, marital status; gender, gender identity or expression; sexual orientation, mental, physical or intellectual disability, veteran status; pregnancy, childbirth or related medical condition; genetic information (including the refusal to submit to genetic testing) or any other class or characteristic protected by applicable law.
Source : Boehringer Ingelheim