Senior Scientist - Analytical Chemistry at Regeneron Pharmaceuticals, Inc.

Regeneron Pharmaceuticals Analytical Chemistry Group is seeking a highly motivated Sr. Scientist to join our group. Sr. Scientists work with LC-MS technologies to guide and support development and characterization of therapeutic protein candidates and other modalities. We apply and solid understanding of various LC-MS platforms and applications to solve analytical problems.

• Design, complete, and optimally communicate analytical characterization of biotherapeutics, including monoclonal and bispecific antibodies, Fc-fusion proteins, and other modalities (adeno-associated virus, mRNA, siRNA, etc.) to support drug discovery and development.
• Lead and deliver on characterization activities to elucidate product quality attributes like post-translational modifications, sequence variants, charge variants, size variants, and host cell proteins.
• Form and maintain inter-departmental collaborations to solve any potential drug development issues.
• We find opportunities to advance LC-MS analysis of biotherapeutics by developing technical innovations that will contribute to future developmental needs and/or efficiency gains.
• Document experiments, results, and findings in electronic laboratory notebook (ELN) entries.
• Present results during internal and external meetings.
• Prepare and review regulatory submission documents like IND, comparability, and BLA reports, as well as manuscripts for publication in peer-reviewed journals.
• Serve as a team representative and provide analytical knowledge and expertise to cross-functional teams.

• You are a critical-thinker and excel at identifying and solving problems.
• You thrive in creative and flexible team environments.
• You are self-motivated and can lead and coordinate multiple projects in a timely manner.
• To be successful in this role, candidates must be detailed, diligent, highly efficient, and capable of collaborating within a team and with external partners. Excellent written and verbal communication skills are essential to this position.

To be considered you must have a BS/MS degree +6 years of experience or a PhD in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or a closely related field, with 2+ years of experience in mass spectrometry-based analysis of proteins and/or other biological molecules (e.g., oligonucleotides, mRNA, lipid nanoparticles, viral vectors). Extensive experience with advanced mass spectrometers (Orbitrap, Q-TOF, Triple Quadrupole, etc.), liquid chromatography, and data processing software (Proteome Discoverer, Skyline, Protein Metrics, MaxQuant, etc.) is desired. Knowledge and hands-on experience in antibody-drug conjugates is a plus.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.

Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.

Salary Range (annually)