Senior Biomarker Scientist at The Fountain Group

The Fountain Group  is a national staffing firm and we are currently seeking a Senior Research Scientist, Immuno-Oncology Biomarker Sciences for a prominent client of ours.  This position is located in Foster City, CA  Details for the position are as follows:
 
Job Description:
Details:

• Pay for this position is 70.00 to 90.97 hourly depending on experience
• This position is a contract with the possibility of extension or conversion to permanent.

• The Biomarker Sciences Department is seeking an experienced, exceptional Senior Research Scientist I to support the Immuno-Oncology therapeutic area. 
• The scientist will will work in a dynamic multidisciplinary matrixed team environment to generate and interpret data from translational and clinical studies. 
• The successful candidate will be responsible for the development and execution of biomarker strategies for programs in the field of immune-oncology for solid tumors. 
• He/she will provide expertise to discovery and development project teams to ensure access to state of the art thinking on appropriate biomarker and diagnostic technologies evaluate their scientific basis and clinical applicability, the validation status and any technical or statistical issues related to the proposed biomarker and/or diagnostic assays. 
• This will include input on clinical protocols and associated documents as well as participation in meetings with regulatory authorities. In addition, the scientist will direct the development, outsourcing and validation of clinically applicable biomarker assays (including pharmacodynamic, predictive, prognostic, and other biomarkers) and design, implement and oversee biomarker and diagnostic testing and data analysis together with the specific functional area representatives. 
• The successful candidate will lead cross functional teams to achieve these aims. 
• Gilead Sciences Inc. is a highly matrixed organization and the ability to work effectively across these groups is a key attribute for this role. 
• Experience in the analysis of multi-dimensional data sets and a strong understanding of mechanisms of immunology and a background in cancer research is highly desirable.

• Direct the development, outsourcing, and validation of clinically applicable biomarker assays including pharmacodynamic, predictive, prognostic, safety and other biomarkers for oncology programs

• Lead cross-functional Biomarker Teams to execute biomarker/diagnostic development strategies to generate, analyze, and interpret data from clinical studies
• Identify, establish and oversee external collaborations with key opinion leaders, academic sites, and CROs to advance our understanding of disease pathways and prognostic/predictive biomarkers
• Collaborate with Research Biology, Clinical Research, Bioinformatics and Biostatistics functions to create synergy in developing biomarker strategies and translational approaches
• Strong experimental background and experience in hypothesis-driven biological/translational research with demonstrated ability to execute well-designed experiments in tumor immunology
• Experience with genomic, epigenetic, gene expression, metabolomics, multiplexed protein detection or other related emerging platforms or data sets is desirable.
• Must be able to work independently and effectively on multiple programs in a fast-paced matrixed environment
• Excellent collaboration, communication, and interpersonal skills are required to engage and be productive within a high achieving team environment
• Must be team and detail-oriented, motivated, and results focused.

• Demonstrated expertise in immunology and/ or oncology clinical development
• Ability to integrate complex scientific ideas, generate testable hypotheses, and execute
• Analysis and interpretation of biomarker data in preclinical and clinical setting
• Broad understanding of drug discovery and development in both early and late stage development and familiarity with regulatory approval process.
• Experience with the discovery, characterization, clinical validation and utilization of innovative biomarkers and potential diagnostics.
• Knowledge of biomarker discovery and development, assay development/validation, clinical discovery of biomarkers, and MoA/translational research.
• Authoring of biomarker strategy documents, biomarker specific portion of clinical protocols, and regulatory documents
• Basic understanding of technical aspects of companion diagnostics development
• Proven scientific/leadership expertise (working in teams, managing people/projects commensurate with level)
• Proven publication record

• PhD and/or post-doctoral training in the area of immunology and/ or oncology or other related medical science field with a minimum of 7 years of directly relevant biotechnology or pharmaceutical industry experience. 
• Candidate must be detail-oriented with excellent record keeping and organizational skills. Must be a highly flexible, results oriented, independent self-starter who enjoys working in a fast paced dynamic multi-disciplinary environment.

 
If you are interested in hearing more about the position please respond to this posting with your resume attached.