Scientist Process Development Engineer - Pfizer
Groton, CT
About the Job
Why Patients Need You
Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.
What You Will Achieve
As a Scientist, you will be at the center of our operations and you’ll find that everything we do, every day, is in line with an unwavering commitment to quality. Your main area of focus will be performing laboratory and pilot-scale process characterization and process optimization studies. You will help Pfizer develop new and improved processes used in the research and development of our drugs. Your innovative mindset will help us develop economical, efficient and safe chemical manufacture of experimental and active drug materials.
You will be part of Chemical Research and Development (CRD), Worldwide R&D in Pharmaceutical Sciences. CRD is responsible for the development of process technology for the production of active pharmaceutical ingredients (API). The Engineer Proc Development Manufacturing are involved in the design and deployment of novel equipment systems for the manufacture of clinical API supplies. The successful candidate is expected to contribute on the design and performance aspects of the manufacturing facilities (equipment, utilities, controls, procedures), while understanding technical capabilities and limitations to properly advise the development and construction of new equipment systems from conceptualization through realization. The candidate collaborates with engineers, chemists, automation, and analysts to develop new equipment prototypes, then works with Global Operations team to implement the new systems in the regulated manufacturing areas.
How You Will Achieve It
Contribute to achievement of goals and influence at the work group/project team level.
Use your technical expertise to manage CRD manufacturing areas, equipment and utilities, the quality systems used in manufacturing, and the composition and workflows of the operations team
Draft, review, and own change records for changes to the process
Author, review, and approve regulated documents that describe key functionality and system configuration
Work on continuous manufacturing initiatives, providing manufacturing and design support into the operation and evolution of API manufacturing platform technologies, such as Plug Flow Reactors, Gas/Liquid Flow Systems, Liquid/Liquid Extraction Systems, Continuous Distillation, Crystallization, Isolation and Drying Technologies and others.
Develop and execute commissioning and validation protocols, standard operating procedures, and cleaning approaches specific to the new equipment systems
Work with Engineering, Operations and Environmental Health & Safety (EHS) representatives to ensure that a scale and facility-relevant Process Safety protocol is used to identify and mitigate safety risks associated with new equipment systems.
Work on process and equipment troubleshooting
Qualifications
Must-Have
Minimum: BS in Chemical Engineering (or relevant engineering discipline) with minimum of 6 years of experience in process engineering/supervision or process development
Excellent oral and written communication skill and a demonstrated ability to work effectively in a multidiscipline team environment.
Nice-to-Have
- knowledge of cGMP and process safety
- Working knowledge of chemical engineering principles including; reaction kinetics, thermodynamics, heat and mass transport, and equipment design.
- Experience using automated flow reactors and associated equipment.
- Experience in authoring laboratory and/or manufacturing process tech transfer instructions.
- Experience with process control systems (Emerson DeltaV, Rockwell, etc..) and historian systems such as Aveva PI for troubleshooting events using historical data
PHYSICAL/MENTAL REQUIREMENTS
Ability to perform complex tasks with appropriate mental agility, including mathematical calculations and complex data analysis.
Working at a computer and manufacturing facilities.
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Occasional international travel maybe necessary to support technology development, clinical manufacturing activities and/or technology transfer to manufacturing.
This position involves integration of novel equipment platforms and processing chemistry steps into a manufacturing environment. During manufacturing runs, there is an expectation that work could be during nights, evenings, and weekends. On occasion it may be necessary to accommodate a planned work schedule that could flex throughout that operating range for start up of projects.
Relocation support available
The annual base salary for this position ranges from $74,900.00 to $128,500.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Research and Development
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