Scientist Oncology Research at Amgen

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Scientist Oncology Research

Lets do this. Lets change the world. The Department of Oncology Research at Amgen, Thousand Oaks is seeking a highly motivated Scientist to contribute to the discovery and validation of novel oncology targets with the goal of supporting the development of Amgens next generation of innovative small-molecule therapeutics. In this vital role you will be an integral member of a dynamic research team, with an opportunity to work collaboratively with cross functional teams within Amgens Discovery Research organization.

The successful candidate is expected to make major scientific laboratory-based contributions to the group goals, present their results in both internal and external forums, and contribute data and participate in the writing of manuscripts for publication.

Specific responsibilities include independently planning and performing laboratory experiments, analyzing data, and communicating results in team meetings. Assay development and routine screening of early-stage drug development candidates may be required.

This is an on-site position which will entail primarily laboratory-based work.

• Assay development, performing experiments

• Analyze data & communicating results to team as well as cross-functionally

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a scientist with these qualifications.

Basic Qualifications:

• Doctorate degree

• Masters degree and 2 years of relevant laboratory experience

• Bachelors degree and 4 years of relevant laboratory experience.

Preferred Qualifications:

• An advanced degree and training in cancer biology or a related field, with a background in cancer signaling pathways and the cell cycle.

• A strong skillset of standard cell and molecular biology experimental design and techniques (e.g. cell culture, western blotting, immunofluorescence, qPCR, flow cytometry, etc). Experience with high-throughput assays (e.g. CTG, AlphaLISA, MSD) is a plus.

• Mammalian cell culture work will be required, and relevant experience is highly desired.

• Experience with modern techniques for assaying gene function (e.g. RNAi and CRISPR approaches), especially lentivirus preparation and utilization

• Familiarity with genomic data analysis suites (DepMap, cBioPortal, OmicSoft).

• Experience in target identification and validation or supporting the early stages of drug discovery.

• A track record of independent critical thinking and scientific achievement, supported by publications and/or significant contributions to a drug discovery program.

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

• Stock-based long-term incentives

• Award-winning time-off plans

• Flexible work models, including remote and hybrid work arrangements, where possible

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.