Research Associate - Senior Research Associate - Oregon Health & Science University

Department Overview:

Overview: The Cancer Early Detection Advanced Research (CEDAR) center is a collaborative institution within the OHSU Knight Cancer Institute. The Knight Cancer Institute, known as one of the pioneers in personalized cancer medicine, is an international leader in research and cancer treatment. At CEDAR our mission is to detect and stop lethal cancers at the earliest stage because early detection saves lives. This is an ambitious goal, one that requires novelty, creativity, and innovation. We are comprised of biologists, chemists, biomedical engineers, computationalists, and clinicians conducting groundbreaking translational cancer research to help people maintain a high quality of life and reduce cancer mortality, to create a global early detection community, and to have a positive impact on the Oregon economy.

 

Our Commitment to Diversity: CEDAR is committed to increasing the diversity of the campus community. We are dedicated to promoting inclusion and multiculturalism by having outstanding researchers of diverse backgrounds work together on multiple projects. We encourage high-risk, high-reward research projects because defeating cancer requires out-of-the-box thinking and new perspectives. Our research is milestone driven to ensure that each project is fulfilling its stated goals.

 

Every Knight Cancer employee is expected to embody our guiding principles:

• We act BOLDLY—Breakthroughs require pushing the boundaries of science, exploring new frontiers, and thinking differently
• We SUPPORT each other—Respect leads to trust, which leads to excellence
• We work as a CONNECTED team—We must leverage our collective brain power to conquer cancer because no one individual can do it alone

Function/Duties of Position:

CEDAR is hiring a talented, motivated and highly interactive Senior Research Associate to participate in our growing electron microscopy (EM) research portfolio. You will use and expand on existing imaging pipelines—from sample preparation, to imaging, to post-processing of 2- and 3-dimensional light and electron microscopy datasets—to identify changes in cellular signaling networks that accompany cancer progression and drug resistance in model systems and clinical specimens.

 

A background in high-resolution EM is necessary, in particular, Scanning Electron Microscopy (SEM), Focused Ion Beam (FIB-SEM) and Transmission Electron Microscopy (TEM). Development and innovation of multi-modal imaging techniques and analyses, i.e. correlative light and electron microscopy (CLEM), will be a central theme of projects. You will be working closely with an interdisciplinary team of biologists, engineers, microscopy experts, and computer scientists to characterize model cancer systems, clinical specimens, “lab-on-a chip” devices, and novel biotechnology using traditional 2D EM and volume EM.

 

This position requires comfort using commercially available software (Amira, Dragonfly, ImageJ, WebKnosses, Napari) and custom-built, deep-learning based software packages to help enable the large-scale image analysis of large EM datasets. Wet lab experience with respect to handling biological specimens and hazardous chemicals is needed. Experience with Python and knowledge of additional imaging modalities, such as confocal, light sheet, multiplexed immunofluorescence and super resolution fluorescence microscopy would be a bonus.

 

Applicants without a demonstrated track record of professional research outputs post-doctoral degree will be considered at the Research Associate level. 

Required Qualifications:

Education & experience:

• SRA: PhD in relevant field and 1 year of relevant experience OR Master’s degree in relevant field and 5 years of relevant experience OR Bachelor’s degree in relevant field and 9 years of relevant experience
• RA: Master’s degree in relevant field and 3 years of relevant experience OR Bachelor’s degree in relevant field and 5 years of relevant experience
• Experience with Scanning Electron and Transmission Electron Microscopy
• General EM sample preparation
• Image post-processing knowledge

Knowledge, skills, and abilities:

• Excellent communication, analytical and organizational skills
• Ability to work independently and as part of a team while being collaborative in resolving problems
• Strong publication record
• Experience handling chemical and biologically hazardous materials
• Knowledge of policy and regulations applicable to the laboratory, including but not limited to safety, animal and radiation
• Technical proficiency, scientific creativity, collaborative ability, and independent thinker
• Must possess energy and drive to coordinate multiple projects simultaneously
• Ability to use tact and diplomacy to maintain effective working relationships
• Ability to operate complex scientific equipment and develop and troubleshoot complex experimental protocols
• Ability to analyze short and long term project needs

Preferred Qualifications:

• 2 or more years in a research position post-doctorate degree, including at least 1 year of project management experience
• Major coursework in the area of Cellular Biology, Materials Science, Engineering, Physics, Chemistry, or similar field
• Cancer Research Experience
• Beginner-level knowledge of Python

Additional Details:

Apply online. Please be sure to upload a Cover Letter and Resume/CV.

 

We offer a variety of benefits on top of joining a thriving organization:

• Medical, dental and vision coverage at no or low cost to employees
  • Covered 100% for full-time employees and 88% for dependents
• Several retirement plans to choose from with contributions from OHSU
• 25 days a year of paid time off
• 8 days of sick time off
• Commuter subsidies
• Tuition reimbursement
• Access to group life insurance, disability insurance and other supplemental benefits
• Annual Merit Increase
• Growth/Development Opportunities
• Employee discounts to local and major businesses  

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All are welcome:Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.