Research Associate III - Protein Engineering at Codexis, Inc.

Department
47 - Protein Engineering

Employment Type
Full Time

Location
Redwood City, CA

Workplace type
Onsite

Description

Codexis, a biotechnology company based in Redwood City, CA, is looking to hire a Research Associate III – Protein Engineering.
 Codexis is a leading enzyme engineering company leveraging its proprietary CodeEvolver® technology platform to discover, develop and enhance novel, high-performance enzymes and other classes of proteins. Codexis enzymes solve for real-world challenges associated with small molecule pharmaceuticals manufacturing and nucleic acid synthesis. The Company is currently developing its proprietary ECO Synthesis™ platform to enable the scaled manufacture of RNAi therapeutics through an enzymatic route. Codexis enzymes can drive improvements, such as higher yields, reduced energy usage and waste generation, improve efficiency in manufacturing and greater sensitivity in genomic and diagnostic applications.  

To meet the goals we’ve set for ourselves, we look for individuals who are driven, eager to grow and ready to embrace meaningful challenges. We empower employees to be authentic, ambitious, agile and have the courage to take action where they can make a positive impact. 

Come join us on this journey to transform the enzyme engineering landscape for the betterment of human health.


About the Opportunity: The Research Associate III – Protein Engineering will join the Protein Engineering group, within the Research department. As a key member, you will be a part of a dynamic and enthusiastic team responsible for engineering of enzymes used in the ECO Synthesis™ platform, for manufacturing of pharmaceutical intermediates, or in Life Science workflows. In this role you will engage in a range of activities with a high performing team with day-to-day laboratory workflows and operations. Your responsibilities will span from designing and building to evaluation of protein libraries, and identifying improved enzyme variants. The position will be based in Redwood City, CA. If any of the below describes you, we would love to meet you!

• Enjoys collaboration across diverse functional teams. 
• Enjoys problem solving and takes initiative seeking ways to implement most efficient workflows. 
• Possesses a passion for being part of the scientific and engineering community, helping bring cutting edge research to enable commercial processes. 

In this role you will be responsible for:

• Generating diverse libraries of enzyme variants through various mutagenesis methods.
• Expressing recombinant protein in high-throughput (HTP) and shake flask scale. 
• Assisting in developing relevant enzyme assays in HTP format.
• Executing HTP screens to evaluate enzyme performance under application-relevant conditions, using UV-Vis Spectrophotometry, CE, HPLC, GC, LC-MS or GC-MS methods to quantify relevant products.
• Managing large data sets and communicating results to a multidisciplinary team.
• Maintaining a safe and efficient workplace, following safe lab practices and organizing lab environment.
• Keeping diligent records and writing reports and SOPs.

The essential requirements of the job include:

• BS or MS in Molecular Biology, Biochemistry, Chemical Engineering, Biotechnology or related scientific field.
• Minimum of 4 years of relevant experience in a laboratory environment.
• Knowledge and interest in molecular biology, protein biochemistry and enzymology.
• Experience with documentation, record keeping, writing SOPs and reports.

Additional experience that would be valuable for this role includes:

• Knowledge of recombinant protein expression techniques within bacterial systems.
• Experience with/understanding analytical techniques.
• Familiarity/ interest in lab automation equipment.

CODEXIS PAY TRANSPARENCY: The anticipated salary range for candidates who will work in Redwood City is $92,250 to $107,000. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc. Codexis is a multi-state employer, and this salary range may not reflect positions that work in other states​.
What can Codexis offer you?

• Medical, Dental and Vision Insurance 
• Basic Life, AD&D, Short- and Long-Term Disability Insurance 
• 401k with Company Match up to 4% 
• Company Equity 
• Generous Paid Time Off including 18 Company Holidays (with a summer and winter shutdown), Vacation, and Wellness Time 
• Annual Lifestyle Account for reimbursement of fitness programs, equipment and more 
• Employee Stock Purchase Program (ESPP) 
• Flexible Spending Accounts (Commuter/Parking, Dependent Care & Healthcare)
• Student Debt Program (Company Contribution to Loans)
• Mental Health Wellness Program
• Subsidized onsite lunch program
• Onsite Gym Facilities
• Paid Parental Leave
• And More!

About Codexis Inc

Why join Codexis?

At Codexis we offer a very competitive compensation package and beyond excellent benefits! We foster career growth, continued education and upskilling through our mentorship program and learning and development opportunities. You will learn and work alongside inspirational leaders and colleagues who are equally passionate about our mission and committed to fostering an inclusive, growth-centered, and rewarding culture. Diversity is valued and mutual trust is of paramount importance to the ethos at Codexis. The people, the culture and working with others with a common goal is what makes Codexis a great place to work.

For more information, visit www.codexis.com.

NO AGENCIES OR THIRD PARTIES

Codexis is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status.