Research Assistant / Senior Research Assistant - Pallando Therapeutics

Company Description

Pallando Therapeutics is pioneering the development of tissue-sparing protein degraders, a transformative approach in targeted therapeutics. We have recently closed an oversubscribed financing round backed by a distinguished group of leading investors.

Job Title: Research Associate/Senior Research Associate, Biology

Job Summary:

We are seeking a highly motivated and skilled Research Associate (RA) or Senior Research Associate (SRA) with extensive experience in mammalian cell culture and cell-based assays. The successful candidate will play a key role in supporting our drug discovery and development programs by executing and optimizing in vitro assays to evaluate target biology and therapeutic candidates. 

Key Responsibilities:

• Perform routine and advanced mammalian cell culture techniques, including maintenance, expansion, and cryopreservation of cell lines (adherent and suspension)

• Develop, optimize, and execute cell-based assays (e.g., viability, proliferation, apoptosis, cytotoxicity, reporter gene, and functional assays) to support drug screening and mechanism-of-action studies

• Utilize techniques such as immunocytochemistry, ELISA, Western blotting, and high-content imaging to analyze cellular responses

• Maintain accurate records of experimental procedures and results in electronic lab notebooks (ELNs) and prepare detailed technical reports

• Present findings to internal stakeholders and participate in team meetings to provide scientific input

• Ensure compliance with laboratory safety protocols and best practices in cell culture and assay development

Required Qualifications:

• Proven expertise in mammalian cell culture techniques, including handling a variety of cell lines and primary cells
• Hands-on experience with cell-based assay development and optimization (e.g., luminescence, fluorescence, colorimetric assays)
• Proficiency in utilizing laboratory instrumentation such as plate readers
• Familiarity with molecular biology techniques such as Western blotting, and transfection methods

Preferred Qualifications:

• Prior industry experience in a biotech or pharmaceutical setting

• Familiarity with data analysis tools such as GraphPad Prism, or image analysis software