Principal Scientist/Associate Director, Immunology at Prellis Biologics, Inc.

Principal Scientist or Associate Director, Immunology

Berkeley, CA

 The Opportunity

The heart of Prellis Bio strategy is the combination of novel, cutting edge methods in machine learning, biology at scale and next gen antibody discovery that address key bottlenecks in the drug development pipeline. To accomplish that, we are putting together an incredible team of discovery biologists, computational scientists, and protein scientists who want to make a difference to this important problem. In this role, you will support the design, development, validation, and implementation of screening assays for the detection of binding and neutralizing anti-drug antibodies (ADAs & NAbs) for Prellis’ large molecule therapeutics to support discovery and GLP preclinical studies.  You will also be responsible to hire and manage outside service partnerships.

You will report to the VP Biology and work a hybrid schedule at our headquarters in Berkeley, CA.

 Your primary responsibilities will include:

• Demonstrated expertise in the development, validation, and oversight of immunogenicity assays for detection of anti-drug binding and neutralizing antibodies according to current global regulatory guidelines
• Experience of working under the Good Laboratory Practices (GLPs)
• Knowledge of statistical approaches applied to immunogenicity assays
• Knowledge of drug-tolerant assay formats for ADA and NAb detection
• Knowledge of cell-based assay formats for NAb detection
• Ability to analyze and interpret data to assist in assay development, validation, and troubleshooting
• Ability to multi-task and manage multiple projects, strong verbal and written communication skills with a high degree of motivation, creativity and collaborative qualities
•  Communicate effectively and collaborate with people of diverse backgrounds and job functions, including a track record of collaborating with life scientists  

You will join a growing and well-positioned biotech startup that is very much in formation. Anticipate a lot can change in this early and exciting phase, providing many opportunities for significant impact. You will work with a very experienced leadership team, learn a broad range of skills, and help shape Prellis Bio's culture, strategic direction, and outcomes. Join us and help make a difference to patients!

About You

• Ph.D. in Biochemistry, Molecular Biology, Cell Biology, Immunology, or a related field with 1-3 years industrial or postdoctoral experience or
• Master’s degree and 5 years of scientific/technical experience or
• Bachelor’s degree and 7 years of scientific/technical experience  About Prellis Biologics

At Prellis we integrate human biology with machine learning. We aim to revolutionized drug discovery by harnessing the power of human immune system with tightly, integrated machine learning to develop next-generation antibody therapeutics with unparalleled speed, precision and safety. We are committed to empowering our pharmaceutical partners with access to the most promising fully human body candidate rapidly identified from the human immune repertoire, enabling them to bring life-changing treatments to patients faster than ever before.  Prellis Biologics is a pre-IPO biotech located in Berkeley CA with a team-oriented, inclusive, and family-friendly culture. Our growing pipeline target high unmet patient needs across therapeutics including metabolic, inflammation, and oncology disease. Prellis has raised funding from top investors, including Celesta, Khosla Ventures, SOSV, & Avidity Partners.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Prellis offers compelling benefits based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A competitive employee benefits package, including group medical, dental and vision coverage, life and disability insurance, flexible spending accounts an a 401(k) plan Stock-based long term incentives Bonus plan Holiday package including a 1+ week winter shutdown Flexible work models, including remote and hybrid working arrangements, where possible

 Application deadline

Prellis does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Prellis Bio is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status

We believe diversity, equity, and inclusion need to be at the foundation of our culture. We work hard to bring together diverse teams–grounded in a wide range of expertise and life experiences–and work even harder to ensure those teams thrive in inclusive, growth-oriented environments supported by equitable company and team practices. All candidates can expect equitable treatment, respect, and fairness throughout the interview process.