Bioinformatics Scientist I/II - Singular Genomics

ABOUT SINGULAR GENOMICS

Singular Genomics is inventing at the forefront of genomics, one of the world's fastest-growing industries. The commercially available G4^® Sequencing Platform is a powerful, highly versatile benchtop genomic sequencer designed to produce fast and accurate results. In addition, the company is currently developing the G4X™ Spatial Sequencer, an upgrade to the G4, which will leverage Singular's proprietary sequencing technology, applying it as an in situ readout for transcriptomics, proteomics and fluorescent H&E in tissue, with spatial context. Singular Genomics' mission is to empower researchers and clinicians to advance science and medicine.

We foster a culture of creativity and technical excellence, both catalysts for innovation. We celebrate diversity, emphasize collaboration and, as we rapidly mature, we are constantly looking at ways we can do better for our people.

Our Headquarters are located on the Torrey Pines Mesa, in La Jolla, California at the center of the biotech hub. Our Manufacturing facility is in Sorrento Valley. This is a Hybrid role that reports to our HQ location.

The Position: As a Bioinformatics Scientist I/II, you will support computational needs for the development and validation of the G4X Spatial platform as well as associated assays. This is a dynamic position that will broaden in scope as the company continues to grow and is ideal for someone who likes to be constantly challenged by new problems. In addition, the ideal candidate excels at multi-tasking and working efficiently to drive projects and results forward with minimal oversight.

Responsibilities: 

• Work closely with a multi-disciplinary team of scientists and engineers to develop tools for in-situ sequencing applications.
• Perform in-depth bioinformatic analyses of in-situ sequencing data.
• Help to develop automated data processing pipelines to support internal R&D work.  
• Document and present approaches and findings to cross-functional teams and management.

Qualifications: 

• Ph.D. in Bioinformatics, Computer Science, Biomedical Science, or related field.  
• A level I candidate will have a PhD + 0-2 yrs of experience; A level II candidate will have a PhD + 2+ yrs of industry and/or Postdoc experience.
• Expertise in single-cell and spatial transcriptomics analyses.
• Experience with analysis of immunohistochemistry or multiplex immunofluorescence assays.
• Understanding of basic image processing algorithms and tasks.
• Proficient in Python and bash scripting.
• Ability to provide interpretable and actionable results from bioinformatic analyses.
• Adept at communicating results to cross-functional teams.
• Independent, motivated, and quick learner.

Desirable Skills: 

• Experience with standardizing, automating, and orchestrating data processing pipelines.
• Experience with HPC-computing and/or cloud computing.
• Understanding of collaborative coding practices (git, version control, CI/CD, documentation).
• Background in immuno-oncology research.
• Familiarity with machine learning approaches.
• Experience with standard NGS analysis methodologies and tools.

The estimated base salary range for a Scientist 1 based in the United States of America is: $79,500 - $121,400. The estimated base salary range for a Scientist 2 based in the United States of America is: $94,600 - $133,200. Compensation decisions are dependent on several factors including, but not limited to, an individual's qualifications, location where the role is to be performed, internal equity, and alignment with market data. Should the level of the role change during the hiring process, the applicable salary range may be updated accordingly. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package.

Singular Genomics is an equal-opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

Singular Genomics is committed to working with and providing reasonable accommodations to job applicants with physical or mental disabilities. Applicants with a disability who require a reasonable accommodation for any part of the application or hiring process can provide their name and contact information to our Accommodations team at accommodationsrequest@singulargenomics.com. Your request will be responded to as soon as possible.

Please note: Singular Genomics does not accept agency resumes and is not responsible for any fees related to unsolicited resumes. Please do not forward resumes to Singular Genomics employees.