Senior Research Associate_SAN-DDD-06-27 at Software Galaxy Systems, LLC
Waltham, MA 02451
About the Job
Duration: 06 Months
- Fully Onsite: We are seeking a highly motivated and scientifically rigorous individual to join the Delivery and formulation development team. The position will focus on developing novel lipid nanoparticle (LNP) formulations for mRNA delivery.
Responsibilities: - Prepare formulations and perform characterization assays/data analysis with focus on in vivo studies, drug carrier design/development, assay development etc.
- Support vaccine formulation development activities.
- Contribute to the development & writing/reviewing analytical method protocols.
- Prepare technical reports and presentations for clear communication of scientific findings across interdisciplinary teams.
Qualifications:
- B.S./M.S. in Biomedical Eng./Chemistry/Physical Chemistry/Chemical Engineering/Biochemistry
- 3+ years of relevant experience in nucleic acid delivery with hands-on experience in lipid nanoparticle (LNP) formulations & characterization is a must
- Direct experience with messenger RNA
- encapsulation/quantification/characterization/handling is required
- Understanding and success in implementation of RNA-related analytics (rib green, gel electrophoresis, capillary electrophoresis, etc.) is required
- Proficiency in analytical techniques like HPLC/UPLC, DLS, CD, zeta potential, UV-Vis and fluorescence spectrophotometry etc. is preferred
- Experience in developing LNP formulations for gene/cell immunotherapy would be advantageous
- Works collaboratively within group as well as within interdisciplinary teams
- Manages time effectively demonstrating ability to perform multiple projects at one time
- Desire to work in a fast-paced environment
- Excellent organizational and communication skills
- Strong analytical and problem-solving skills
Must Have: 3+ years of relevant experience in nucleic acid delivery with hands-on experience in lipid nanoparticle (LNP) formulations & characterization is a must
- Direct experience with messenger RNA encapsulation/quantification/characterization/handling is required
- Understanding and success in implementation of RNA-related analytics (Rib green, gel electrophoresis, capillary electrophoresis, etc.) is required
Nice to Have:
- Proficiency in analytical techniques like HPLC/UPLC, DLS, CD, zeta potential, UV-Vis and fluorescence spectrophotometry etc. is preferred
- Gene Therapy and or proficiency in the above
- Master's degree is a plus