Scientist/Senior Scientist, Powder Characterization - Bristol Myers Squibb
Summit, NJ
About the Job
Working with Us
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .
Business Unit and Team Summary
Our Drug Product Development team is committed to CMC design, development, and commercialization of innovative drug products to improve patient lives. We leverage the best people, collaboration, and cutting-edge innovation to achieve this commitment. BMS's internal engine of innovation includes unrivaled industry leading expertise in CMC development of small molecules, protein biotherapeutics, protein degraders, and other therapeutic modalities. We collaborate closely with our colleagues in R&D and Commercial to design our drug products. Here, you'll get the chance to grow and thrive through opportunities that are uncommon in scale and scope.
Position Summary
Materials Science & Engineering (MSE) in Drug Product Development (DPD) plays an integral role in the development and characterization of powder materials used in various applications and building robust form and powder property control strategies of the active pharmaceutical ingredient (API) in the drug product.
The Powder Characterization Scientist/Senior Scientist will be responsible for characterization of particle and powder properties to guide robust drug substance and drug product development throughout all stages of development (from discovery to commercialization). Primary activities will include characterization of materials properties such as particle size, surface area, and morphology, as well as method development, validation, and transfer. It is expected that the candidate will work with a broad range of materials, including crystalline and non-crystalline small molecule APIs, drug product intermediates and excipients, and biologics.
The Scientist/Senior Scientist will be responsible for building powder property knowledge (linking powder properties to drug substance and product processability and quality attributes), identifying critical quality attributes and proposing powder property control strategies. Strong communication, interpersonal and leadership skills are key since the scientist will operate within cross-functional teams.
Key job responsibilities
+ Conduct comprehensive analysis and characterization of powder materials, including particle size distribution, morphology, surface area, density, flowability, and other relevant properties using various techniques.
+ Design and execute experiments to evaluate the physical and chemical properties of powders, utilizing appropriate techniques and equipment (laser light scattering, image analysis, surface area, optical and electron microscopy, sieving)
+ Collaborate with cross-functional teams to provide technical expertise and support in selection, processing, and optimization of powder materials for specific applications.
+ Stay updated with the latest advancements and trends in powder science and engineering and apply this knowledge to enhance our research and development activities.
+ Generate accurate and detailed reports, documenting experimental procedures, results, and conclusions.
+ Support analytical method development, optimization, troubleshooting, transfer, validation.
+ Contribute to the development of new methodologies and techniques for powder characterization and analysis.
+ Assist in the scale-up and manufacturing processes of powder-based products, ensuring quality and consistency.
+ Collaborate with external partners, such as vendors and academic institutions, to leverage their expertise and resources for powder-related projects.
+ Maintain a safe and organized laboratory environment, adhering to all relevant safety protocols and guidelines
Requirements
+ (Scientist) Ph.D. and minimum of 0-2 years of experience or MS and minimum of 2-4 years of experience
+ (Senior Scientist) Ph.D. and minimum of 2-4 years of experience or MS and minimum of 4-6 years of experience
+ Knowledge of powder properties, solid state characterization techniques and relevant analytical instruments.
+ Knowledge of drug substance and drug product manufacturing processes as well as knowledge of other bulk characterization techniques (such as powder flow, rheology, friability, stickiness etc) is a plus.
+ Effective communication and collaboration skills to work within and lead cross-functional teams.
+ Understand and apply Quality by Design and DOE approaches when required.
+ Excellent problem-solving skills and ability to troubleshoot experimental challenges?
+ Hands-on experience with unknown material and/or foreign particulates identification is a plus
+ Detail-oriented with strong organizational and documentation skills.
+ Ability to adapt to changing priorities and work in a fast-paced environment
+ Knowledge of other solid state characterization techniques (such as vibrational spectroscopy, crystallography, SSNMR, vapor sorption, XRD, TGA, DSC) is a plus.
+ This position requires employees to work with or come in contact with chemical agents which may pose health or safety hazards if improperly handled.
#GPSProdDev
If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as Transforming patients' lives through science™ , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
On-site Protocol
BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ (https://careers.bms.com/eeo-accessibility) eeo-accessibility to access our complete Equal Employment Opportunity statement.
BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
Company: Bristol-Myers Squibb
Req Number: R1586912
Updated: 2024-12-20 05:18:34.835 UTC
Location: Summit West-NJ
Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .
Business Unit and Team Summary
Our Drug Product Development team is committed to CMC design, development, and commercialization of innovative drug products to improve patient lives. We leverage the best people, collaboration, and cutting-edge innovation to achieve this commitment. BMS's internal engine of innovation includes unrivaled industry leading expertise in CMC development of small molecules, protein biotherapeutics, protein degraders, and other therapeutic modalities. We collaborate closely with our colleagues in R&D and Commercial to design our drug products. Here, you'll get the chance to grow and thrive through opportunities that are uncommon in scale and scope.
Position Summary
Materials Science & Engineering (MSE) in Drug Product Development (DPD) plays an integral role in the development and characterization of powder materials used in various applications and building robust form and powder property control strategies of the active pharmaceutical ingredient (API) in the drug product.
The Powder Characterization Scientist/Senior Scientist will be responsible for characterization of particle and powder properties to guide robust drug substance and drug product development throughout all stages of development (from discovery to commercialization). Primary activities will include characterization of materials properties such as particle size, surface area, and morphology, as well as method development, validation, and transfer. It is expected that the candidate will work with a broad range of materials, including crystalline and non-crystalline small molecule APIs, drug product intermediates and excipients, and biologics.
The Scientist/Senior Scientist will be responsible for building powder property knowledge (linking powder properties to drug substance and product processability and quality attributes), identifying critical quality attributes and proposing powder property control strategies. Strong communication, interpersonal and leadership skills are key since the scientist will operate within cross-functional teams.
Key job responsibilities
+ Conduct comprehensive analysis and characterization of powder materials, including particle size distribution, morphology, surface area, density, flowability, and other relevant properties using various techniques.
+ Design and execute experiments to evaluate the physical and chemical properties of powders, utilizing appropriate techniques and equipment (laser light scattering, image analysis, surface area, optical and electron microscopy, sieving)
+ Collaborate with cross-functional teams to provide technical expertise and support in selection, processing, and optimization of powder materials for specific applications.
+ Stay updated with the latest advancements and trends in powder science and engineering and apply this knowledge to enhance our research and development activities.
+ Generate accurate and detailed reports, documenting experimental procedures, results, and conclusions.
+ Support analytical method development, optimization, troubleshooting, transfer, validation.
+ Contribute to the development of new methodologies and techniques for powder characterization and analysis.
+ Assist in the scale-up and manufacturing processes of powder-based products, ensuring quality and consistency.
+ Collaborate with external partners, such as vendors and academic institutions, to leverage their expertise and resources for powder-related projects.
+ Maintain a safe and organized laboratory environment, adhering to all relevant safety protocols and guidelines
Requirements
+ (Scientist) Ph.D. and minimum of 0-2 years of experience or MS and minimum of 2-4 years of experience
+ (Senior Scientist) Ph.D. and minimum of 2-4 years of experience or MS and minimum of 4-6 years of experience
+ Knowledge of powder properties, solid state characterization techniques and relevant analytical instruments.
+ Knowledge of drug substance and drug product manufacturing processes as well as knowledge of other bulk characterization techniques (such as powder flow, rheology, friability, stickiness etc) is a plus.
+ Effective communication and collaboration skills to work within and lead cross-functional teams.
+ Understand and apply Quality by Design and DOE approaches when required.
+ Excellent problem-solving skills and ability to troubleshoot experimental challenges?
+ Hands-on experience with unknown material and/or foreign particulates identification is a plus
+ Detail-oriented with strong organizational and documentation skills.
+ Ability to adapt to changing priorities and work in a fast-paced environment
+ Knowledge of other solid state characterization techniques (such as vibrational spectroscopy, crystallography, SSNMR, vapor sorption, XRD, TGA, DSC) is a plus.
+ This position requires employees to work with or come in contact with chemical agents which may pose health or safety hazards if improperly handled.
#GPSProdDev
If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as Transforming patients' lives through science™ , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
On-site Protocol
BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ (https://careers.bms.com/eeo-accessibility) eeo-accessibility to access our complete Equal Employment Opportunity statement.
BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
Company: Bristol-Myers Squibb
Req Number: R1586912
Updated: 2024-12-20 05:18:34.835 UTC
Location: Summit West-NJ
Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.
Source : Bristol Myers Squibb