Research Associate II - Sequencing and Molecular Biology - AlivaMab Discovery Services
San Diego, CA 92121
About the Job
AlivaMab Biologics is seeking an outstanding individual to join the Antibody Engineering Team. The successful applicant will have the responsibility to support antibody discovery and engineering projects through Next-Generation Sequencing (NGS) of various samples including, but not limited to, hybridomas, single B-cells, immune repertoires, and phage libraries. The individual will also perform molecular cloning and contribute to technology development in the Molecular Biology group. This position will report to the Principal Scientist, Sequencing and Molecular Biology, and work closely with scientists in the Protein Sciences and Antibody Discovery teams.
AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab® Mouse suite of transgenic mice. We excel in the rapid and efficient delivery of molecularly diverse therapeutic antibody candidates, well-characterized for function, kinetics, and developability, with expanding capabilities for engineering advanced modalities, including multispecifics, single-domain human VH antibodies, and CARs. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science.
Responsibilities:Responsibilities
- Execute NGS workflow from sample submission to sequencing analysis
- Perform data analyses and report generation (bioinformatics experience is a plus)
- Further optimize NGS workflow, troubleshoot when needed, and identify areas for improvement
- Work in close collaboration with stakeholders and project managers to address operational needs
- Document the work promptly and accurately using Electronic Lab Notebook and generate protocols and SOPs
- Manage and maintain operation inventory and lab supply
- Keep up with routine maintenance of NGS and other lab instruments
Qualifications
- BS in Molecular Biology, Biomedical Engineering, or a related scientific field with a minimum of 3 years of relevant industry experience; or MS degree with 1-3 years of experience.
- Experience with NGS workflows and sequencing
- Experience with molecular cloning is preferred
- Ability to improve and streamline existing processes
- Operationally minded with ability to summarize and track workflow status and performance
- Highly organized including time management, planning, and documentation
- Self-motivated with the ability to work with and support multiple groups across the organization
- Experience using electronic lab notebook services (specifically Benchling is a plus).
- Prior experience in Bioinformatics and automation is a plus
About AlivaMab Biologics
AlivaMab Biologics sets its partners’ antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners’ design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team’s experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab® Mouse platforms, ensure the highest probability of success.
AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.
The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual’s circumstances. The current estimated range is $66,500 – $87,000, plus a bonus target, benefits, and equity.
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