Medical Director (Early Clinical Development) at Novo Nordisk
Lexington, MA
About the Job
About the Department
The Global Nucleic Acid Therapies area strives to be a global leader in nucleic acid therapeutics by developing innovative technology platforms and molecules that translate into novel genetic medicines to improve patients' lives.Our mission is to bring curative and disease modifying therapies to individuals living with serious chronic conditions. We are a global team with locations in Massachusetts (Greater Boston Research & Early Development Hub), Colorado and Copenhagen, pushing technological innovation to expand the RNA and gene therapy application space. Our proprietary GalXC™ and GalXC-Plus™ RNAi technologies have the potential to address conditions that are difficult or impossible to treat with other modalities. The value chain spans from early research to phase 1 clinical studies.
Established as a Transformational Research Unit (TRU), Global Nucleic Acid Therapies is a unique organization within Novo Nordisk Research & Early Development that brings together the best of both worlds – the agility, collaborative pioneering spirit and calculated risk-taking profile of a biotech along with the scale, resources and capabilities of a global leader in drug development. We are a team of inventive and entrepreneurial thinkers pushing the boundaries of science. Together, we are driving change. Are you ready to make a difference
The Position
The Novo Nordisk GNAT (Global Nucleic Acid Therapies) Early Development Unit is seeking a Medical Doctor with a high degree of scientific acumen, as well as clinical care and drug development experience who is excited by cutting-edge biotechnology and wishes to take part in the unique opportunity to bring highly innovative pharmaceutical products through early clinical development. The candidate is a team player, detail oriented with prior research experience, ideally both in academic medicine and in pharma or biotech.
In this role, the incumbent will assist the team in the GNAT Early Development Unit to advance siRNA oligonucleotide molecules into clinical development. In doing so, they will work across diverse functional teams to plan, design, execute, and analyze early clinical trials, especially first-in-human (FIH) trials. They will be part of a small but dynamic GNAT Medical and Science group, with an emphasis on planning trials that address both initial human safety as well as proof-of-concept that assesses potential efficacy of the drug candidate. The role will entail highly diverse skills, including strategic direction of the GNAT drug candidates, as well as serving as the medical lead for several early development programs. In this high-visibility position, the candidate will be interfacing with both internal and external stakeholders including GNAT and Novo Nordisk senior leadership, external clinical experts, and Principal Investigators.
Relationships
Reports to: Senior Medical Director, GNAT Early Clinical Development.
Work with the Early Development Medical and Science group and the entire GNAT Early Development (ED) team, including the VP of Early Development, GNAT Project Vice-Presidents (PVPs), Program Management, Non-clinical Research, Pharmacology, Toxicology, RNAi Chemistry Manufacturing and Controls (CMC) staff and other functions. Collaborate and interface with relevant functions in the Novo Nordisk US Clinical Development Group, whose functions include Drug Safety, Regulatory Affairs, Clinical Operations, Medical Writing, Biostatistics, Data Management and other functions. Work collaboratively as required with the global Novo Nordisk drug development organization, including the NNI US corporate hub in New Jersey and world headquarters in Denmark.
Essential Functions
Physical Requirements
Approximately 5-10% overnight travel. Ability to lift 0-10 lbs.
Development of People
Supervisory
Ensure that reporting personnel have individual development plans (IDP), with annual goals and measurements that are consistent with the priorities of the business, and that interim reviews are held so that their work is focused on those priorities, and they understand their level of accountability for results and the measurement process.
Ensure that the IDP forms include completed learning and aspiration plans and are in place for all reporting personnel to enable the achievement of goals and capability to assume increased levels of responsibility.
Manage the application and communication of all Novo Nordisk policies, procedures, and Novo Nordisk Way.
Qualifications
We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.
At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.
Novo Nordisk is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status or any other characteristic protected by local, state or federal laws, rules or regulations.
If you are interested in applying to Novo Nordisk and need special assistance or an accommodation to apply, please call us at 1-855-411-5290. This contact is for accommodation requests only and cannot be used to inquire about the status of applications.